Long story short, no, she should be able to take off her mask and be okay with Shepard again if she prepares properly.

The situation where she reveals her face might be similar to that, only this time the camera doesn't give us the middle finger. As soon as he took off her mask, the camera moved away and didnt show her face. But again - Tali practiced safe kissing with Shepard. If a Quarian were to just remove their mask without being prepared for it, there's a good chance they'd have a life-threatening cold. Though it was still a heavy risk, even with all the medical aid and Mordin's terrific booklet of sex advice for Shepard.

The next time you talk to her, she says she has a horrible fever - but was worth it. But it's kinda implied they got pretty intimate. Granted it never shows more than removing her mask then kissing, followed by them both fully dressed laying in bed cuddling. In 2183, she is on her Pilgrimage, the rite of passage to prove her worth. Born on the vessel Rayya among the Migrant Fleet, she is the daughter of Admiral RaelZorah, a member of the Admiralty Board.Despite being young, Tali is considered a mechanical genius. In ME2, if you're male Shepard and choose her as the love interest, she mentions she had to take a lot of herbal supplements and immunoboosters before they got together. TaliZorah vas Neema nar Rayya (later vas Normandy and vas Rannoch) is a young quarian and a member of Commander John Shepards squad.

Tali without her mask